The Honourable Dame Quentin Bryce AD CVO, Hon DUniv (Griffith), patron of The Perry Cross Spinal Research Foundation together with the Spinal Injury Project team unveiled the Phasefocus Livecyte microscope and plaque at the Griffith Institute for Drug Discovery, in a celebration of cutting-edge research and technological innovation.

The microscope represents a significant advancement in scientific instrumentation and is set to revolutionise the Spinal Injury Project undertaken by the Clem Jones Centre for Neurobiology and Stem Cell Research at Griffith University.

It will enable the research team to perform critical cell analysis and screening procedures, a crucial step toward the cell transplantation and rehabilitation human clinical trials commencing shortly.

The clinical trial aims to test cell transplantation therapy to repair spinal cord injury, ultimately leading to the restoration of function.

Professor James St John said the advanced microscope is new to the market and offers the capability to track the fate of each cell through high-resolution live cell imaging.

“Livecyte allows for the identification of any cells exhibiting abnormalities or likely to cause complications such as tumour formation. By screening the cells that are prepared for the patient, and ensuring the cells are healthy, we can decrease the risk of adverse events for the patients. The livecyte microscope will play a pivotal role in ensuring the safety of the cells used in the transplantation process.”

READ FULL ARTICLE HERE

We would like to congratulate our colleagues and friends at the Ingham Institute for Applied Medical Research, Liverpool NSW, and wish them well for the awards night to be held on Tuesday- 24 October 2023. The NSW Health Awards recognise personalised, sustainable, and digitally enabled health programs that deliver outcomes that matter most to patients and invest in the wellness of the NSW community.

Electron microscopy plays a major role in diagnosing disease, however high costs can limit its access. NSW Health Pathology’s Liverpool lab assessed electron microscopy platforms, such as the Phenom Pharos, to see if they could be modified to increase automation and be more cost-effective. The team worked with ATA Scientific and Thermo Fisher Scientific International for this project. Together, they reimagined a low-cost benchtop electron microscope, used for engineering and geology, for use in pathology. It will be used in NSW Health Pathology Anatomical laboratories and has global commercial potential.

This new class of electron microscopy can resolve single proteins, viruses and key cellular changes in renal disease, cancer and rare diseases. This offers wide-ranging health and economic benefits for patients and the NSW Health system.

In a world-first trial, a prototype was produced and assessed by NSW Health Pathology’s Liverpool lab. Results were presented at the 20th International Microscopy Congress in September. A second prototype is being developed by Thermo Fisher in the UK to provide enhancements essential to replace existing EM technology currently in use.

For more infomation on how the desktop Phenom Pharos FEG-SEM with low kV STEM imaging may be used for fine high resolution ultrastructural characterisation of soft tissues for cell biology and pathology, view application note here.

Low-kV STEM imaging of soft tissues for cell biology and pathology

Scanning electron microscopy as a new tool for diagnostic pathology and cell biology – ScienceDirect

Most journeys in scientific research begin with curiosity and a hunger to make a meaningful impact on humanity. Here Dr Woojeong Kim, a passionate researcher at the UNSW in the field of food science and engineering, shares her inspiring journey and remarkable contributions made in the realm of food research.

From utilising traditional Chinese food for novel applications to revolutionising protein analysis with cutting-edge technology, Kim and her research group are driving a food transformation as the world looks for a more sustainable food system that tastes good too. This article explores Kim’s journey into science, her passion for research, and the transformative role of microfluidic modulation spectroscopy (MMS by RedShiftBio) in her work.

To read the full article click the link below

Advancing food science with microfluidic modulation spectroscopy (labonline.com.au)

RUX Energy is an advanced materials company delivering breakthrough improvements in hydrogen storage and distribution. Their Micromeritics ASAP system is providing key insight into hydrogen adsorption capacity. It enables the team to conduct quick high throughput gas sorption analysis, with the capacity to degas 12 samples and run 6 samples at once on the one instrument.

To read the full article, click here

We are excited to announce that the Perry Cross Research Foundation have been able to fund the first piece of equipment to be used as part of the Cell Transplantation and Rehabilitation Human Clinical Trial – the PhaseFocus LiveCyte Microscope!

The Livecyte will support The Spinal Injury Project (SIP) at the Menzies Health Institute Queensland (MHIQ) and the Griffith Institute for Drug Discovery (GRIDD) at Griffith University where the research team provides ground-breaking and world-first research into curing paralysis.

Live cell imaging is a powerful technique for the study of cultured mammalian cells, and crucial for establishing cell identity and behaviour – essential for cell transplantation. But the exposure to light and the need to label cells with chemical markers in conventional live cell imaging techniques can have toxic effects on the cells. Therefore, characterising individual cells in preparation for transplantation without impacting their health and behaviour is a significant challenge.

The Phasefocus Livecyte uses a technique called ptychographic quantitative phase imaging. This technique generates high-contrast, detailed images of live cells using low-powered illumination instead of harsh light, and does not require chemical labelling of the cells. The Livecyte is also equipped with a fully enclosed temperature-controlled incubation unit with a controller for carbon dioxide and humidity to ensure that the cells remain stable, viable and healthy over the imaging period (days-weeks). Thus, it is much gentler on the cells than any other live cell microscopy technique.

The Livecyte will help overcome the challenge of characterising cells before transplantation without causing damage, as it allows label-free and non-invasive long-term imaging. In addition, critical attributes of the cells such as individual cell behaviour, morphology and migration capacity over time can be monitored with high specificity using the Livecyte. Cells derived from tissues are a mixture of different cell types.

Tracking individual cells will help determine the exact cell composition and heterogeneity of the cell population. The Livecyte system has automated single-cell tracking algorithms with an integrated analysis suite making it easy to measure the motion and morphology of every cell. Specific cell sub-populations can be identified, and can stratify groups of cells from a complex cell culture based on their behaviour. A unique fingerprint for each cell and a comprehensive profile of its dynamics within the entire cell population is generated.

This information will improve our understanding of how each cell behaves within the environment of the actual transplant and will be a realistic measure of cell characteristics.

Livecyte is set to become the gold standard in clinical cell transplantation therapies allowing cell preparations with a considerably increased safety profile.

For more information or to arrange a demo, contact us.

Original article source: Human Clinical Trial Equipment Purchase | PCSRF | To Cure Paralysis for All

We are pleased to announce ATA Scientific has entered an exciting new partnership with Hauschild SpeedMixer®, expanding capabilities to provide high-performance laboratory mixing equipment for Australia and New Zealand.

For over fifty years, Hauschild SpeedMixer® have been the go-to choice for businesses requiring high-quality, reliable laboratory mixing solutions. The Dual Asymmetric Centrifuge (DAC) technology developed by Hauschild makes it possible to combine seemingly impossible substance mixtures, enabling new product ideas to come to life. With this latest expansion of their sales network, Hauschild is now able to contribute to the success and future viability of companies located in Australia and New Zealand through expert advice and support provided on location.

Fabio Boccola, CEO of Hauschild, expressed his enthusiasm about the partnership: “I am very pleased with the latest expansion of our sales network. This enables us to now also contribute to the success and future viability of companies located in these countries, providing competent advice and support provided on location. We do already have some of our products installed on in Australia but with the support of ATA Scientific we will be acting much more local, being certainly able to offer an even greater service.”

ATA Scientific, a leading supplier of advanced scientific instruments and analytical services, will serve as the exclusive distributor for Hauschild SpeedMixer® products in Australia and New Zealand. Their expertise in various industries such as particle size analysis, zeta potential measurements, rheological testing, and more make them a perfect partner for distributing Hauschild’s long-established laboratory mixing equipment.

Bryn McDonagh, the Director of ATA Scientific, furthermore explains: “We are familiar with the DAC technology and its advantages and know that it will enhance the daily work of our customers that are already working in the laboratory segments. As such we are confident that this line of product will add great value to the current offering of our products and services to both our existing and potential new customers.”

The collaboration between Hauschild Engineering and ATA Scientific represents a significant milestone in expanding access to innovative laboratory mixing solutions across the globe. Together, they aim to provide businesses in Australia and New Zealand with the tools they need to develop new materials and drive their industries forward.

The latest innovation of Hauschild – the Hauschild SpeedMixer® SMART DAC is now also available in Australia and New Zealand

About Hauschild Engineering:

The family-owned company Hauschild Engineering employs around 40 people and has been developing and producing the Hauschild SpeedMixer® at its headquarters in Hamm/Germany since 1974, selling it directly or with partners all over the world.
The original Hauschild SpeedMixer® offers perfect mixing results from a few grams or milliliters up to ten kilograms or sixteen liters. The machines are mostly used in laboratories that mix substances as part of their research and development work, as well as by companies that require small batch mixes for quality assurance.
Within few minutes, different liquids can be mixed with pastes or powders, pastes with powders, powders with powders, and substances with different chemical and physical properties – all without the use of stirring tools. The Hauschild SpeedMixer®, including all components, are manufactured according to a highest-quality standards – made in Germany.

Hauschild YouTube channel: https://www.youtube.com/channel/UCs9jdLhro1rPgRZ3Lr-Nu1A/videos

Info at www.hauschild-speedmixer.comhttp://www.hauschild-speedmixer.com

Contact us for more information or to book your personal demonstration!!