ATA Scientific provides a unique set of analysis tools that enable rapid, robust and confident decision-making at all stages of pharmaceutical development and manufacturing. Our technologies can reduce the time, cost and risk associated with each stage.
Several key attributes such as particle size, shape and chemical identity or molecular weight, size, concentration and binding kinetics help to advance understanding of pharmaceutical formulation requirements. They contribute to a successful drug development program and form a foundation for creating drugs to address unmet medical needs today and in the future.

Below are the latest recorded webinars focused on these measurements 

DOWNLOAD OUR QUICK GUIDE HERE   Grating Coupled Interferometry  This webinar will discuss how binding kinetics supports Peptide Discovery processes using the Creoptix WAVEsystem WATCH NOW UPLC & multi-detector SEC in one One platform provides Absolute MW (no column calibration needed), aggregation, composition, CQAs for AAVs – e.g. viral titre, % full rAAV  WATCH NOW   Automated Image Analysis Do you have problems getting your powders to flow or dissolve? If so, using automated image analysis to investigate particle shape could help you overcome these challenges! WATCH NOW Laser Diffraction This webinar will explore ways of setting particle sizing requirements for active pharmaceutical ingredients (APIs) during oral solid dosage product development. WATCH NOW   Isothermal Titration Calorimetry Tips for success: This webinar will discuss the best practices for using organic solvents with Isothermal Titration Calorimetry (MicroCal ITC). WATCH NOW Light scattering & X-ray imaging This webinar will help you understand the role of deformulation prior to a bioequivalence study, detection of APIs and excipients.  WATCH NOW     WANT MORE?  For a full overview of the 2022 webinar program, click here.  To watch any of last year’s webinars, take a look at the full program recordings here.

We are looking for a service engineer to support these advanced technology instruments. This is a multi-skilled role combining fault finding, repairing and calibrating instruments and training operators.

• High tech analytical instrumentation and scientific equipment
• Wide variety of jobs and activities
• Southern Sydney (Sutherland Shire) location

ATA Scientific specialises in selling and servicing analytical and scientific instruments.

See www.atascientific.com.au

Required Qualifications.

• Degree/diploma in electronics or instrumentation.
• Several years of practical experience in fault diagnosis, repair (to component level) and maintenance of electronic systems or instruments.
• Ideally also familiarity with optics, fluidics and computer control.
• An excellent command of written and spoken English.
• Good presentation skills with the ability to conduct training courses.
• Computer skills in both office and technical software systems.
• Valid motor car license.
• Ability to travel occasionally interstate and overseas.
• Citizen of Australia with current Australian passport or Permanent resident with a visa with minimum of 3 years of unlimited return into Australia.

This position will suite you if you enjoy working in the scientific community. There will be a high degree of autonomy, however it is also important that you also like working within a small team. As well as having the above Qualifications you will need to be methodical and accurate at reporting and record keeping.

Location.     

Office and workshop are located in Taren Point, Sutherland Shire, Sydney. You must reside within a reasonable commuting distance, preferably less than 45 minutes.

Remuneration.

A package to attract the right person, including salary, Company car, superannuation, and expenses. There will be the statutory probationary period.

Interviews – commencing time.

Interviews will be conducted around the end of April 2022. Commencing time is flexible, preferably by the end of May 2022.

How to Apply.  Do not phone

Please e-mail your CV to The Recruiting Manager tmcdonagh@atascientific.com.au

Alternatively Post to The Recruiting manager, ATA Scientific PO Box 2172, Taren Point 2229.

SECURING MRNA MANUFACTURING FACILITIES IN AUSTRALIA

The Australian RNA Production Consortium (ARPC) has been featured as one of Australia’s game-changers for 2021 in the Sydney Morning Herald article, “Who Mattered 2021“. The RNA biomedical experts of ARPC, including Professor Thomas Preiss at the John Curtin School of Medical Research, ANU, are praised for their effort in securing mRNA manufacturing facilities in Australia. ATA Scientific is proud to be supporting the ARPC initiative. If you would like further information or require assistance please contact us.       UNSW RNA Institute (RNAI), has officially launched  The UNSW RNA Institute (RNAI), Australia’s leading RNA science, therapeutics, and translational facility, has officially opened.  Countless hours of planning and developing have transpired, now Director of the Institute, Professor Pall Thordarson says “the RNA revolution is just getting started”. How can we help? ATA Scientific are determined to the establishment a network of scale-up platforms throughout Australia to service the growing research need to translate drug candidates through to the clinic. Contact ATA Scientific for more information about the NanoAssemblr range, request a demo or a meeting to discuss your project. Call Peter Davis 0417 778 971 or email pdavis@atascientific.com.au.   READ THE FULL ARTICLE HERE

Accelerated Development of Self-amplifying mRNA (saRNA) Vaccines using Microfluidics   Read more here   Scale Up & Manufacturing of SaRNA-LNPs for a COVID-19 Vaccine Using NanoAssemblr GMP System     Read more here   Effects of Polymeric and Lipid Nanoparticle SaRNA on Protein Expression and Vaccine Immunology   Watch webinar

Woojeong Kim, a PhD student from the School of Chemical Engineering, University of New South Wales (UNSW) under the guidance of Professor Cordelia Selomulya and Dr. Yong Wang, was recently selected from an overwhelming number of submissions to receive the first RedShiftBio StructIR Lab Grant.

“I’m glad that Woojeong has the opportunity to use microfluidic modulation spectroscopy for her project and look forward to the interesting outcomes” said Professor Cordelia Selomulya

The group works on particle and drying technologies in food and dairy formulations, in particular, emulsion stabilisation mechanisms, powder production using spray drying, and computational modelling to improve the process and properties of particles and powders.

This highly competitive grant announced in October 2021, will fund Woojeong’s current research project through sample testing and analysis with access to RedShiftBio’s StructIR Lab. Staffed by a dedicated scientific team of experts, the facility houses several of the company’s flagship AQS³pro instruments. Known for its ground-breaking novel Microfluidic Modulation Spectroscopy (MMS) technology, the AQS3pro overcomes many of the limitations of traditional spectroscopy-based technologies.

“I feel honoured to receive this grant and am excited to share new knowledge from this work, especially in characterising complex food formulations. I would like to express special gratitude to Dr. Yong Wang who let me know about this grant”, said Woojeong.

Woojeong’s PhD project aims to improve the functionalities of plant proteins using protein blends from different food sources, particularly focusing on protein interaction, structural modification, and food application including encapsulation and powder production. The emerging trend towards clean-label food products containing natural ingredients in food industry drew her attention to work on utilising food proteins as natural emulsifiers, ultimately enhancing the functionality and shelf lives of food ingredients and products with minimal processing. Studies have shown that the addition of alginate, a polysaccharide, improves the stability of binary whey/pea protein-stabilised emulsions by enabling protein fractions to be attached at the oil/water interface for a long storage period. Currently, Woojeong is exploring protein interactions between pea and whey protein and developing binary protein-based wall materials that can maximise emulsifying properties and encapsulate nutrients efficiently. Her plan is to apply the designed systems to food products in various formulations such as gels, emulsions, and powders. Using MMS, Woojeong hopes to resolve the shortcomings of Fourier-Transform Infrared Spectroscopy (FT-IR) or Circular Dichroism  (CD) in examining the secondary structures of proteins.

“Protein structural analysis is a very important part of my project, as common characterisation methods were not sufficient to analyse my samples…. MMS technology has the potential to provide a breakthrough in detecting protein aggregation and structural similarity. Measuring the original samples without dilution is a major advantage of this technology given the instrument can cover a wide range of sample concentrations (0.1-200 mg/mL)” said Woojeong.

In FT-IR analyses, moisture has to be removed via freeze-drying, while the sample forms a protein film, which can cause structural deformation. In addition, protein solution samples are prepared at relatively low concentrations meaning the absorbance of the protein complexes can fall below the detection limit. For CD, the method is regarded a low-resolution technique, which requires significant dilution of the samples and a limited selection of buffers that may affect the accuracy of results.

Never before have scientists been able to analyse the secondary structure of proteins and other large molecules so easily, quickly, and effectively until now. MMS provides ultrasensitive, highly reproducible, automated structural measurements of proteins and other biomolecules. Able to differentiate <2% change in HOS, the technique can be used for a wide range of applications from formulation development of mAb-based biotherapeutics to robust measurements of ADCs, AAVs, and mRNA.

The company is also announcing a second StructIR Lab Grant program specific for Australia/NZ – Please register your interest to apply.

For further details please contact us,

ATA Scientific Pty Ltd

www.atascientific.com.au

or Email Peter Davis: pdavis@atascientific.com.au