02 9541 3500Malvern Morphologi 4
Malvern Morphologi 4 rapidly measures particle size, shape, transparency, count and location of dry powders, fibres and wet suspensions using automated static imaging analysis.
Malvern Morphologi 4
Malvern Morphologi 4 rapidly measures particle size, shape, transparency, count and location of dry powders, fibres and wet suspensions using automated static imaging analysis.
| Manufacturer | Malvern Panalytical |
|---|---|
| Product Series | Malvern Morphologi |
| Measurement principle | Microscopy - Image Analysis |
| Application | Particle Shape, Count & Chemical ID |
| Sample type | Powders, suspensions, fibres |
| Particle size range | 0.5µm to >1300µm |
| Particle size parameters | Circle equivalent diameter, length, width, perimeter, area, max distance, sphere equivalent vol, fiber total length, fiber width |
| Particle shape parameters | Aspect ratio, circularity, convexity, elongation, high sensitivity circularity, solidity, fibre elongation, fibre straightness |
| Integrated Sample Dispersion | Fully automated dispersion with SOP control of dispersion pressure, injection time and settling time |
| Detector | 18 MP; 4912 x 3684 pixel colour CCD array; pixel size 1.25 μm x 1.25 μm |
Product Overview
The Malvern Morphologi 4 is an easy-to- use, automated particle characterisation tool for the measurement of particle size, shape and count. It is the ideal replacement for costly and time-consuming manual microscopy measurements.
The integrated dry powder disperser simplifies sample preparation by allowing representative sampling and good particle separation. Using compressed air, a small amount of sample is dispersed automatically to ensure any strongly agglomerated materials are evenly distributed while avoiding the damage of fragile particles. Effective dispersion of fibres can also be achieved.
The Morphologi 4 uses a powerful microscope with an integrated high signal to noise CCD camera to provide the highest quality images. Every measurement has calibration checks for camera pixel size and sample illumination intensity providing repeatable and robust methods. The user can also return to a selected particle for a more in depth analysis at higher or lower magnifications.
A choice of accessories supports analysis of samples on microscope slides, in wet suspensions or on membrane filters. The Morphologi 4-ID includes a Raman microprobe, which gains the additional ability to chemically identify particles and foreign contaminants.
The software provides simple operation with automatic selection, targeting and rapid chemical classification of thousands of individual particles. Automated and unattended, the Standard Operating Procedure (SOP) approach delivers substantial time savings by allowing users to get on with other tasks while the instrument completes the measurements.
- Demonstration video
- Benefits
- Applications
- Accessories
Demonstration video
Benefits
Simple automated operation
The integrated dry powder dispersion option ensures representative sampling and optimal spatial separation while avoiding damage of fragile particles.
High quality measurements for both dry and wet samples and particulates on filter membranes
Every measurement has calibration checks for camera pixel size and sample illumination intensity for repeatable and robust methods. The user can return to a selected particle for a more in depth analysis at higher or lower magnifications. ‘Sharp Edge’ analysis enables detection of even low contrast particles. 21 CFR Part 11 software option ensures regulatory compliance.
Saves time and frees up resources
Intuitive software provides simple operation with auto selection, targeting and rapid chemical classification of thousands of individual particles. The SOP approach delivers time savings by allowing for unattended operation.
Applications
- Automation of microscopy methods, eg detection of foreign particulates
- Crystallisation engineering and formulation development
- Discovery/R&D screening tool with only mg of sample needed
- Troubleshooting and root cause analysis in manufacturing
- Validation of QC particle sizing methods, e.g laser diffraction
Accessories
For analysis of particles in suspension
2-slide and 4-slide holder
Allows a few μL of a particulate suspension to be presented using either the 2-slide or 4-slide holder.
Wet dispersion cell
Allows between 2 mL and 6 mL of sample for characterising larger suspended particles or where volumetric particle count is important.
Thin-path wet cell
It is ideal for applications such as the identification of subvisible particles (upto 100μL) in therapeutics described by guidance in USP <787> and USP <788>.
25 mm and 47 mm diameter filter holders
Allow samples on filter membranes to be presented directly to the instrument for analysis.
Fused silica filters and holder
Enable the analysis of filtered samples containing low-contrast particles such as
protein aggregates or contaminant particles.
Twin 35 mm petri dish holder
Provides an alternative means of measuring suspended particles that may be at
risk of being deformed when dispersed into a cell.
Make Product Enquiry
Related products
Malvern Morphologi 4-ID
Malvern Morphologi 4-ID combines automated static imaging for particle size, shape, count with Raman Spectroscopy to enable additional chemical identification analysis.
Find out more
Malvern Mastersizer 3000+ Ultra
The Malvern Mastersizer 3000+ Ultra is the most advanced particle sizing system with integrated AI technology that enables effortless and reliable measurement of particle size distribution for both wet and dry dispersions with full automation and robot options.
Find out moreProduct Enquiry
SPEAK TO OUR AUSTRALIAN AND NEW ZEALAND TEAM
If you would like to enquire about this product, fill out this form and one of our product specialists will contact you shortly.
If you need help in the operation or repair of an instrument then please contact the Customer Help Centre directly.
Please note, product enquiries are only applicable to Australia, New Zealand, Papua New Guinea and Fiji
Or call us instead at (02) 9541 3500